Fifty-eight species of mosses (37 genera, 18 families( and 4 species of liverworts (3 genera, 3 families) are reported from Konza Prairie Research Natural Area, a 3,487 hectare tallgrass prairie preserve in northeastern Kansas. Factors affecting the growth and persistence of bryophytes on the prairie are discussed. The occurrence of bryophytes in presettlement tallgrass prairies was probably influenced by natural disturbance due to grazing and recurring fire